HNMT anticorps (C-Term)
Aperçu rapide pour HNMT anticorps (C-Term) (ABIN5516047)
Antigène
Voir toutes HNMT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- SGWDKLWKKY GSRFPQDDLC QYITSDDLTQ MLDNLGLKYE CYDLLSTMDI
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Attributs du produit
- This is a rabbit polyclonal antibody against HNMT. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human HNMT
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HNMT (Histamine N-Methyltransferase (HNMT))
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Autre désignation
- HNMT
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Sujet
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In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: HNMT,
Protein Interaction Partner: CAMK2D, DSP, TINF2, POT1, TERF1,
Protein Size: 292 -
ID gène
- 3176
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NCBI Accession
- NP_008826
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UniProt
- P50135
Antigène
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